Lilit Nersisyan

This paper introduces s5PSeq, a streamlined protocol for rapid antimicrobial sensitivity testing using 5P mRNA degradation intermediates, demonstrating its clinical utility in identifying resistant Clostridioides difficile isolates.

The paper shows that ribosomes modulate transcriptome abundance through frameshifts and out-of-frame mRNA decay in yeast under poor nutritional conditions, with conservation across species.

The paper analyzes honeybee gut microbiome variation across regions and pesticide effects using metagenomics and co-abundance networks, finding stable core taxa and pesticide-induced functional shifts.

The paper analyzes RNA degradation in microbiome samples to study ribosome dynamics and species-specific responses to stress and drugs.

The paper analyzes telomere maintenance pathway activities in human tissues to identify gene-level and tissue-specific patterns of telomerase and ALT pathway activation.

The paper introduces fivepseq, a tool for analyzing 5P degradome data, revealing insights into ribosome dynamics and gene-specific features in yeast and Arabidopsis.

The paper develops a computational framework to reconstruct telomere maintenance pathways and assess their activity using gene expression data and literature.