Aoi Ichiyama

This study identifies recurrent inhibition as a key circuit motif regulating functional states of stress effector neurons through experimental and computational approaches.

This study investigates how second-scale neural dynamics in CRH neurons translate stress signals into sustained hormonal outputs, showing firing rate over seconds determines CRH release.

This study identifies a mechanism by which CRH neurons in the hypothalamus switch between activity states in response to stress, using electrophysiology and computational modeling.

The paper shows that repeated stress reduces intrinsic excitability of HPA axis neurons through increased cell size and membrane area, challenging conventional views on excitability plasticity.