Ling Zhang

Paired-probe chemoproteomic strategy enables global site-resolved quantification of lysine redox states

The paper introduces PRISM-Lys, a chemoproteomic method to quantitatively map lysine redox states, revealing site-specific changes during ferroptosis.

Cyclic uremia without kidney injury drives cardiovascular disease with rapid onset of immunosenescence and heart failure

This study establishes a mouse model of cyclic uremia without kidney injury, showing it drives cardiovascular disease and immunosenescence independently of traditional risk factors.

Ketone Bodies-mediated Cysteine Modifications Discovered by Chemical Proteomics

This study identifies ketone body-mediated cysteine modifications using chemical proteomics, revealing new enzymatic pathways and modifications beyond lysine acylations.

Balancing Growth: GROOT Genes Link Plant Biomass and Temperature Adaptation in Arabidopsis

This study identifies GROOT genes in Arabidopsis that regulate root biomass and temperature adaptation, showing they enhance biomass without negative trade-offs.