A Bioluminescent Activity Dependent Platform, BLADe, for Converting Intracellular Activity to Photoreceptor Activation
Emmanuel L. Crespo, Akash Pal, Mansi Prakash, Alexander D. Silvagnoli, Zohair Zaidi, Manuel Gomez‐Ramirez, Maya O. Tree, Nathan C. Shaner, Diane Lipscombe, Christopher I. Moore, Ute Hochgeschwender
The paper introduces BLADe, a platform that converts intracellular activity into photoreceptor activation using bioluminescent sensors and actuators, demonstrating its use in neurons for activity-dependent gene expression and neural dynamics control.
Scientific Reports · May 11, 2026Peer-reviewedNeuroscience