Author

Alexander D. Silvagnoli

Central Michigan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:benchmarking· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Ashley N. SlavieroiD· 3 shared Emmanuel L. CrespoiD· 3 shared Maya O. Tree· 3 shared Ute HochgeschwenderiD· 3 shared Christopher I. MooreiD· 2 shared Diane LipscombeiD· 2 shared Mansi PrakashiD· 2 shared Nathan C. ShaneriD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersNeuroscience

Ashley N. SlavieroORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Control of Synaptic Communication through Molecularly Engineered Bioluminescence Light Emission and Sensing

Ashley N. Slaviero, Mansi Prakash, Rachel Schumaker, Emmanuel L. Crespo, Alexander D. Silvagnoli, Maya O. Tree, Gerard G. Lambert, Christopher I. Moore, Nathan C. Shaner, Diane Lipscombe, Ute Hochgeschwender

This paper introduces a modular platform called Interluminescence that uses bioluminescent light to control synaptic transmission by activating optogenetic ion channels in postsynaptic neurons.

Communications Biology · Jul 10, 2026Peer-reviewedNeuroscience

A Bioluminescent Activity Dependent Platform, BLADe, for Converting Intracellular Activity to Photoreceptor Activation

Emmanuel L. Crespo, Akash Pal, Mansi Prakash, Alexander D. Silvagnoli, Zohair Zaidi, Manuel Gomez‐Ramirez, Maya O. Tree, Nathan C. Shaner, Diane Lipscombe, Christopher I. Moore, Ute Hochgeschwender

The paper introduces BLADe, a platform that converts intracellular activity into photoreceptor activation using bioluminescent sensors and actuators, demonstrating its use in neurons for activity-dependent gene expression and neural dynamics control.

Scientific Reports · May 11, 2026Peer-reviewedNeuroscience

Presymptomatic Targeted Circuit Manipulation for Ameliorating Huntington's Disease Pathogenesis

Ebenezer C Ikefuama, Ashley N. Slaviero, Alexander D. Silvagnoli, Emmanuel L. Crespo, Raegan Schalau, Madison L Gott, Maya O. Tree, Gary Leo Dunbar, Julien Rossignol, Ute Hochgeschwender

The paper investigates presymptomatic manipulation of cortical neuron activity in HD mice to restore E/I balance and slow disease progression.

iScience · Feb 13, 2025Peer-reviewedNeuroscience

A Method for Optimizing Imaging Parameters to Record Neuronal and Cellular Activity at Depth with Bioluminescence

Alexander D. Silvagnoli, Kaylee A. Taylor, Ashley N. Slaviero, Eric D. Petersen

The paper develops an in vitro method to optimize imaging parameters for bioluminescence-based neuronal activity recording without animal use.

Neurophotonics · Mar 28, 2024Peer-reviewedNeuroscience