NeuroscienceCell ReportsPeer-reviewed
Autism risk gene POGZ promotes chromatin accessibility and expression of clustered synaptic genes
Eirene Markenscoff-Papadimitriou, Fadya Binyameen, Sean Whalen…·John L.R. Rubenstein
The paper shows POGZ promotes chromatin accessibility and expression of synaptic genes in mouse and human brains, and its reduction disrupts cortical function through interactions with ADNP.