Christian L. Lorson

This paper describes a mouse model of SMARD1 with severe respiratory and feeding deficits, demonstrating milk aspiration and reduced survival.

This study creates and characterizes Nefl E397K mouse models of CMT2E, showing early axonal neuropathy and electrophysiological abnormalities.

This paper characterizes motor function deficits, muscle pathology, and breathing abnormalities in NeflE397K mice, showing progressive disease severity with genotype.

The paper identifies and evaluates two potent SARS-CoV-2 entry inhibitors through computational screening and in vitro testing, showing synergy with remdesivir.

The paper identifies factors contributing to the higher infectivity of SARS-CoV-2 variants using bioinformatics and structural analysis.

The paper describes a splicing modifier compound that creates a tunable mouse model of spinal muscular atrophy, showing efficacy in preventing and reversing SMA phenotypes with short-term treatment.