Author

Panagiotis A. Konstantinopoulos

Brigham and Women's HospitalORCID 0000-0002-1032-1479Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alan D. D’AndreaiD· 1 shared Aleem SyediD· 1 shared Bartłomiej TomasikiD· 1 shared Bose S. KochupurakkaliD· 1 shared Changli Qian· 1 shared Dipanjan ChowdhuryiD· 1 shared Elena V. IvanovaiD· 1 shared Erica M. HoldridgeiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Alan D. D’AndreaORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedMay 4, 2026

Targeting FGFR signaling overcomes therapeutic resistance and immune evasion in oncogenic PIK3CA-driven serous-like endometrial cancer

Xin Cheng, Y Zhang, Changli Qian…·Jean J. Zhao

This study identifies FGFR signaling as a driver of resistance and immune evasion in PIK3CA-driven serous-like endometrial cancer and shows that dual FGFR/PI3K inhibition improves tumor control.

DOI 10.1038/s41467-026-72544-z

mousebulk RNA-seq

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Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedSep 11, 2023

Dynamics of the DYNLL1/MRE11 complex regulates DNA end resection and recruitment of the Shieldin complex to DSBs

Michelle L. Swift, Rui Zhou, Aleem Syed…·Dipanjan Chowdhury

This study shows how DYNLL1 and Shieldin regulate DNA end resection and repair pathway choice through interactions with MRE11 and 53BP1 at DSBs.

27 citations

humanexperimental assay

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