Author

Elena V. Ivanova

Brigham and Women's HospitalORCID 0000-0002-5069-4974Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Bose S. KochupurakkaliD· 1 shared Celia Torres-AranciviaiD· 1 shared Changli Qian· 1 shared Cloud Peter PaweletziD· 1 shared David Allen BarbieiD· 1 shared Erica M. HoldridgeiD· 1 shared Geoffrey Ira ShapiroiD· 1 shared Gordon James FreemaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Bose S. KochupurakkalORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 20, 2026

A dynamic molecular glue targets a plastic MDA5 filament interface to stimulate innate immunity

闫丽娟, 闫丽娟, Ziqing Ye…·Sun Hur

This paper identifies MA2, a small-molecule agonist of MDA5 that enhances antiviral and antitumor immunity by dynamically stabilizing MDA5 filaments.

DOI 10.64898/2026.10.14.759171

humanexperimental assay

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Cancer BiologyNature CommunicationsPeer-reviewedMay 4, 2026

Targeting FGFR signaling overcomes therapeutic resistance and immune evasion in oncogenic PIK3CA-driven serous-like endometrial cancer

Xin Cheng, Y Zhang, Changli Qian…·Jean J. Zhao

This study identifies FGFR signaling as a driver of resistance and immune evasion in PIK3CA-driven serous-like endometrial cancer and shows that dual FGFR/PI3K inhibition improves tumor control.

DOI 10.1038/s41467-026-72544-z

mousebulk RNA-seq

𝕏 PostBluesky