Author

Dylan Valleau

Whitehead Institute for Biomedical ResearchORCID 0000-0002-1067-9067Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:electrophysiology· 1

Frequent Co-Authors

Frances MaleiD· 2 shared Gary E. WardiD· 2 shared Sebastian LouridoiD· 2 shared Irene Jiménez-MunguíaiD· 1 shared Joshua J. ZimmerbergiD· 1 shared Justin M. RobertsiD· 1 shared Maryse LebruniD· 1 shared Mudita Goyal· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Frances MaleORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 16, 2025

Clustering of host N-glycans licenses Toxoplasma rhoptry discharge

Dylan Valleau, Mudita Goyal, Justin M. Roberts…·Sebastian Lourido

The paper identifies host N-glycosylation and cholesterol biosynthesis as required for Toxoplasma rhoptry discharge, mediated by the MIC1/4/6 complex clustering host factors.

DOI 10.1101/2025.10.16.682961

humanexperimental assay

MicrobiologyEMBO ReportsPeer-reviewedSep 19, 2025

Perforation of the host cell plasma membrane during Toxoplasma gondii invasion requires rhoptry exocytosis

Frances Male, Yuto Kegawa, Paul S. Blank…·Gary E. Ward

This study confirms that Toxoplasma gondii induces a transient increase in host cell plasma membrane conductance during invasion, suggesting a perforation mechanism for rhoptry protein delivery.

3 citations

humanelectrophysiology