Author

Irene Jiménez-Munguía

National Institutes of HealthORCID 0000-0003-1588-9511Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:electrophysiology· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

Frances MaleiD· 2 shared Gary E. WardiD· 2 shared Joshua J. ZimmerbergiD· 2 shared Paul S. BlankiD· 2 shared Yuto KegawaiD· 2 shared Dylan ValleauiD· 1 shared Elena MekhedoviD· 1 shared Maryse LebruniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMicrobiology

Frances MaleORCID

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2 papers

Recent·Most cited

MicrobiologyEMBO ReportsPeer-reviewedSep 19, 2025

Perforation of the host cell plasma membrane during Toxoplasma gondii invasion requires rhoptry exocytosis

Frances Male, Yuto Kegawa, Paul S. Blank…·Gary E. Ward

This study confirms that Toxoplasma gondii induces a transient increase in host cell plasma membrane conductance during invasion, suggesting a perforation mechanism for rhoptry protein delivery.

3 citations

humanelectrophysiology

𝕏 PostBluesky

BiophysicsEMBO ReportsPeer-reviewedSep 19, 2025

The invasion pore induced by Toxoplasma gondii

Yuto Kegawa, Frances Male, Irene Jiménez-Munguía…·Joshua J. Zimmerberg

The paper identifies a transient membrane conductance increase in host cells induced by Toxoplasma gondii, which precedes invasion and is termed the invasion pore.

2 citations

humanelectrophysiology

𝕏 PostBluesky