Ryuichi Ono

This paper introduces bridge recombinase for versatile genome editing in bacteria, achieving large insertions, inversions, and excisions across multiple phyla and gut communities.

This study shows that knocking out Rtl8a and Rtl8b in mice leads to reduced social behavior, increased apathy, and obesity, likely due to decreased GABRB2 expression in the brain.

This study shows that Rtl8a and Rtl8b double knockout mice develop late-onset obesity and neurodevelopmental defects, indicating these retrovirus-derived genes are important for brain function.

This study shows that disrupting the viral aspartic protease domain in PEG10 causes placental abnormalities and perinatal lethality in mice.