James R. Reynolds

The paper shows that sensory experience increases glutamate release and strengthens synaptic connections in the barrel cortex, leading to changes in the functional connectome.

The paper shows that sensory-stimulation LTP increases synaptic fidelity while reducing excitation at thalamocortical connections, generating spatially intersecting glutamate discharges.

The paper shows that release probability increases with distance from the soma in CA3-CA1 synapses, enhancing signal transfer fidelity at higher frequencies.

This study shows that LTP induces astroglial withdrawal, increasing glutamate spillover and inter-synaptic communication.

This study uses multiplexed multiphoton imaging to examine the relationship between synaptic activity and astroglial responses in the intact brain, finding that astrocytic Ca2+ elevations often precede presynaptic Ca2+ signals.

The paper constructs a realistic multi-compartmental astrocyte model to explore its biophysical properties and uncover features inaccessible through empirical methods.