Igor Kraev

The paper shows that HCN channel dysfunction is linked to tauopathies, with altered synaptic structure and function in Alzheimer's and Tau35 mouse models.

This study shows that ECM attenuation increases synapse number but suppresses synaptic plasticity by reducing neuronal excitability and impairing LTP.

This study shows that LTP induces astroglial withdrawal, increasing glutamate spillover and inter-synaptic communication.

The paper constructs a realistic multi-compartmental astrocyte model to explore its biophysical properties and uncover features inaccessible through empirical methods.