Steven B. Bradfute

An ONT sequencing framework for hantavirus genome assembly, variant analysis, and defective viral genome characterization from whole-segment amplicons

This paper introduces an Oxford Nanopore sequencing framework for hantavirus genome assembly and variant analysis, revealing defective viral genomes as a new feature of hantavirus populations.

Burning down the mouse: Effects of wildfire and post-fire reseeding on Sin Nombre virus prevalence in its reservoir host

This study examines how wildfire and post-fire reseeding affect Sin Nombre virus prevalence in western deer mice, finding higher prevalence in reseeded sites and increased transmission linked to resource pulses from reseeding and ENSO cycles.

SARS-CoV-2 ORF3a blocks lysosomal cholesterol egress by disrupting VPS39-regulated NPC2 trafficking and BMP metabolism

This study shows SARS-CoV-2 ORF3a disrupts lysosomal cholesterol export by interfering with VPS39-regulated NPC2 trafficking and BMP metabolism.

Identification of host lncRNAs that impact Venezuelan equine encephalitis virus replication

The paper identifies lncRNAs that influence VEEV replication in mouse astrocytes, showing that suppressing Snhg15 increases viral replication and affects antiviral gene expression.