BioengineeringJournal of Controlled ReleasePeer-reviewed
Collagen targeting IL-12 combined with Doxorubicin enhances the anti-tumor effect against osteosarcoma
Takumi Matsuo, Laurine Noblecourt, Pooja Kaur…·Jun Ishihara
This study combines collagen-targeted IL-12 with doxorubicin to improve anti-tumor effects in osteosarcoma by enhancing tumor accumulation and immune activation.
DOI 10.1016/j.jconrel.2026.115414