Paul A. MacAry

This paper identifies an IFNγ-CXCL9-CXCR3 axis linking T cell recruitment to skeletal muscle remodelling in human physical frailty, showing its association with fibrosis and potential therapeutic targets.

This study shows that antibodies against Mtb enhance immunity via NLRP3 inflammasome activation in mice, independent of Fc receptors, and this mechanism applies to polyclonal sera in rhesus macaques.

A nasal booster vaccine candidate induced cross-clade, durable, systemic and mucosal immunity in mRNA-vaccinated mice, offering superior protection against emerging sarbecoviruses.

This study shows that N153-linked glycans on dengue virus envelope protein help evade antibody-mediated clearance, with implications for immune evasion in related flaviviruses.