Genetic & Genomic MedicinemedRxivPreprint
A foundational neuronal protein network model unifying multimodal genetic, transcriptional, and proteomic perturbations in schizophrenia.
Greta Pintacuda, Yu-Han H. Hsu, Petra Páleníková…·Kasper Lage
The paper identifies three neuron-specific schizophrenia protein networks enriched for genetic and transcriptional perturbations and validates their disruption in 22q11.2 deletion carriers.
DOI 10.1101/2025.05.02.25326757