This study analyzes genetic diversity and evolution of European swine influenza A viruses from 2013 to 2022, identifying 150 genotypes and highlighting pig trade as a driver of viral spread.

bioRxiv · Sep 25, 2026 · PreprintMicrobiology

Pseudotyped virus-based platform and structural analysis reveal potential cross-reactivity sites between influenza C and D viruses

Maria Marotta, Shahid Rowles-Khalid, Martin Mayora Neto, Janet M. Daly, Pauline M. van Diemen, Helen Everett, Emanuele Montomoli, Claudia Maria Trombetta, Nigel James Temperton, Kelly da Costa

The paper uses pseudotyped viruses and structural analysis to identify shared antigenic sites between influenza C and D viruses, suggesting potential for cross-protective vaccines.

bioRxiv · Jul 20, 2026 · PreprintImmunology

Diverse Genomic Landscape of Swine Influenza A Virus in England (2014 - 2021)

Benjamin C. Mollett, Alexander Byrne, Helen Everett, Scott M. Reid, Susanna Williamson, Tavis K. Anderson, Joe James, Ashley C. Banyard, Ian Hay Brown, Nicola S. Lewis

This study analyzes Swine Influenza A Virus (SwIAV) genomic diversity in England from 2014 to 2021, identifying new HA clades and genotypes within the 1B lineage.

Microbial Genomics · Mar 19, 2026Peer-reviewedGenomics

Isothermal Detection of Influenza D using RT-LAMP

Carlos Abelardo dos Santos, Jialu Li, Pauline M. van Diemen, Andrew McMahon, Benjamin C. Mollett, Andrew M. Ramsay, Meshach Maina, Joe James, Helen Everett, Janet Mary Daly, Nicole C. Robb

The paper develops and validates an RT-LAMP assay for detecting influenza D virus with high specificity and sensitivity, offering a cost-effective alternative to RT-qPCR for field use.

bioRxiv · Jan 9, 2026 · PreprintMicrobiology

Experimental infection of alpacas (Vicugna pacos) with Influenza C and D viruses results in subclinical upper respiratory tract disease

Pauline M. van Diemen, Andrew M. Ramsay, Helen Everett, Shellene Hurley, Fabian Z. X. Lean, Alejandro Núñez, Rebecca Callaway, Adrien Lion, Maria Gaudino, Aurélie Sécula, Fatima‐Zohra Sikht, Gilles Meyer, Mariette Ducatez

This study infects alpacas with Influenza C and D viruses, showing subclinical upper respiratory tract infection and suggesting a potential role for camelids in virus ecology.

Journal of General Virology · Dec 12, 2025Peer-reviewedMicrobiology

Immunogenicity and Efficacy of Digitally Immune Optimised H1N1 Vaccine Candidates in Swine and Murine Animal Models

Joanne Marie M. Del Rosario, Pauline M. van Diemen, Simon D. W. Frost, Sneha Vishwanath, Sneha B Sujit, Sruthika K. Ashokan, Benjamin C. Mollett, Andrew M. Ramsay, Benjamin Scott S Simpson, Benedikt Asbach, George Carnell, Andrew Chan, Paul Tonks, Nigel James Temperton, Matthew Davies, , Jonathan Luke Heeney

This paper demonstrates the immunogenicity and efficacy of a computationally designed DNA vaccine against H1N1 influenza in swine and mice, showing broad neutralizing antibody responses and reduced viral shedding.

bioRxiv · Sep 12, 2025 · PreprintImmunology

Development and optimisation of Influenza C and Influenza D pseudotyped viruses

Maria Marotta, Martin Mayora Neto, Janet M. Daly, Meshach Maina, Pauline M. van Diemen, Helen Everett, Maria Stella Lucente, Michele Camero, Emanuele Montomoli, Claudia Maria Trombetta, Kelly da Costa, Nigel James Temperton

The paper develops and optimizes pseudotyped viruses for influenza C and D to enable antiviral screening and sero-epidemiological studies.

Journal of Virological Methods · Aug 23, 2025Peer-reviewedImmunology