Author

Eijiro Shimada

Duke UniversityORCID 0000-0002-1244-3584Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Benjamin Aaron AlmaniD· 2 shared Choiselle Marius· 2 shared Koji IshikawaiD· 2 shared Tuyet NguyeniD· 2 shared Vijitha Puviindran· 2 shared Jiaul Hoque· 1 shared Koki AbeiD· 1 shared Mahoko Ishikawa· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Benjamin Aaron AlmanORCID

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2 papers

Recent·Most cited

Age-Dependent Effects of Macrophage Derived Cathelicidin Antimicrobial Peptide on Bone Fracture Repair

Tuyet Nguyen, Yasuhito Yahara, Eijiro Shimada, Vijitha Puviindran, Vijitha Puviindran, Koji Ishikawa, Choiselle Marius, Benjamin Aaron Alman

This study identifies cathelicidin antimicrobial peptide (CAMP) as an age-dependent regulator of bone fracture repair, showing it promotes healing in young mice but limits it in aged mice through P2X7R-NLRP3 signaling.

bioRxiv · Sep 30, 2026 · PreprintCell Biology

Muscle-to-Bone CX3CL1 Signaling Promotes Skeletal Repair Through CX3CR1+ Osteoprogenitors

Koji Ishikawa, Choiselle Marius, Eijiro Shimada, Puvi Nadesan, Tuyet Nguyen, Mahoko Ishikawa, Jiaul Hoque, Xinyi Ma, Makoto Nakagawa, N ALLEN, Koki Abe, Philip Varnadore, Tomokazu Souma, Shyni Varghese, Yasuhiro Yahara, , Benjamin Aaron Alman

This study identifies a muscle-to-bone signaling pathway where CX3CL1 from muscle endothelial cells promotes bone repair via CX3CR1-expressing osteoprogenitors.

bioRxiv · May 27, 2026 · PreprintCell Biology