Benjamin Aaron Alman

This study identifies cathelicidin antimicrobial peptide (CAMP) as an age-dependent regulator of bone fracture repair, showing it promotes healing in young mice but limits it in aged mice through P2X7R-NLRP3 signaling.

This study identifies a muscle-to-bone signaling pathway where CX3CL1 from muscle endothelial cells promotes bone repair via CX3CR1-expressing osteoprogenitors.