Andy J. Chang

The paper identifies AP-1's role in regulating distinct ECM programs during lung development and fibrosis, showing its potential as a therapeutic target.

This study identifies declining Wnt signaling as a driver of age-related alveolar stem cell loss and shows that restoring Wnt signaling in aged mice improves lung repair but not full regeneration.

This study uses heterochronic myeloid cell replacement to show that the local brain environment, not intrinsic factors, drives microglia aging.