Johannes Riegler

The paper identifies AP-1's role in regulating distinct ECM programs during lung development and fibrosis, showing its potential as a therapeutic target.

This study identifies declining Wnt signaling as a driver of age-related alveolar stem cell loss and shows that restoring Wnt signaling in aged mice improves lung repair but not full regeneration.

The paper uses genetic correlation analysis in DO mice to identify QTL and candidate genes linked to age-related pathologies.

This study examines how caloric restriction and intermittent fasting interact with genetics to influence physiological health in mice, finding diet-specific effects and significant genetic contributions to multiple traits.

This study shows that endothelial CXCL12 is crucial for neovascularization in tissue repair and tumor progression by regulating endothelial-fibroblast interactions and recruiting neovascularization-supporting cells.