Author

David N. Boone

University of PittsburghORCID 0000-0002-1258-7473Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Adrian V. LeeiD· 2 shared David M. GauiD· 2 shared Ian EderiD· 2 shared Partha Sarathi RoyiD· 2 shared Pooja A. ChawlaiD· 2 shared Virginia Yu· 2 shared Adriana T. LarreginaiD· 1 shared Deborah Lynn GalsoniD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Adrian V. LeeORCID

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2 papers

Recent·Most cited

Cancer BiologyMolecular Biology of the CellPeer-reviewedDec 4, 2024

Breast cancer cells promote osteoclast differentiation in an MRTF-dependent paracrine manner

Pooja A. Chawla, Ishani Sharma, David M. Gau…·Partha Sarathi Roy

This study shows that MRTF in breast cancer cells promotes osteoclast differentiation via paracrine signaling, enhancing bone metastasis, and suggests MRTF inhibition as a potential therapeutic strategy.

3 citations

humanexperimental assay

𝕏 PostBluesky

Cell BiologyMolecular Biology of the CellPeer-reviewedAug 28, 2024

mDia2 is an important mediator of MRTF-A-dependent regulation of breast cancer cell migration

Ian Eder, Virginia Yu, Jacob Antonello…·Partha Sarathi Roy

This study identifies mDia2 as a mediator of MRTF-A-dependent breast cancer cell migration and links MRTF activity to malignancy, suggesting it as a therapeutic target.

8 citations

humanproteomics

𝕏 PostBluesky