Molecular BiologyNature CommunicationsPeer-reviewed
Altered tRNA processing is linked to a distinct and unusual La protein in Tetrahymena thermophila
Kyra Kerkhofs, Jyoti Garg, Étienne Fafard-Couture…·Mark A. Bayfield
The paper shows that Tetrahymena thermophila's Mlp1, lacking the RRM1 domain, functions as a La protein and alters tRNA processing by stabilizing 3-trailers and preventing leader/trailer pairing.
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