Author

Hyunmin Lee

University of TorontoORCID 0000-0002-7970-2050Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Edyta Marcon· 3 shared Jack F. GreenblattiD· 3 shared Nujhat Ahmed· 3 shared Shuye PuiD· 3 shared Syed Nabeel‐ShahiD· 3 shared Zhaolei ZhangiD· 3 shared Benjamin J. BlencoweiD· 2 shared Giovanni L. BurkeiD· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Edyta Marcon

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Recruitment of the m6A/Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48

Syed Nabeel‐Shah, Shuye Pu, Giovanni L. Burke, Nujhat Ahmed, Ulrich Braunschweig, Shaghayegh Farhangmehr, Hyunmin Lee, Mingkun Wu, Zuyao Ni, Hua Tang, Guoqing Zhong, Edyta Marcon, Zhaolei Zhang, Benjamin J. Blencowe, Jack F. Greenblatt

This study identifies ZBTB48 as a regulator of FTO's substrate selectivity by facilitating its binding to m6A/m6Am-containing RNAs, affecting RNA decay and cancer cell growth.

Genome biology · Sep 19, 2024Peer-reviewedMolecular Biology

SARS-CoV-2 Nucleocapsid protein attenuates stress granule formation and alters gene expression via direct interaction with host mRNAs

Syed Nabeel‐Shah, Hyunmin Lee, Nujhat Ahmed, Giovanni L. Burke, Shaghayegh Farhangmehr, Kanwal Ashraf, Shuye Pu, Ulrich Braunschweig, Guoqing Zhong, Hong Wei, Hua Tang, Jianyi Yang, Edyta Marcon, Benjamin J. Blencowe, Zhaolei Zhang, Jack F. Greenblatt

This study identifies SARS-CoV-2 N protein interactions with host proteins and mRNAs, showing it attenuates stress granule formation and alters gene expression.

iScience · Dec 4, 2021Peer-reviewedMolecular Biology

Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila

Syed Nabeel‐Shah, Jyoti Garg, Alejandro Saettone, Kanwal Ashraf, Hyunmin Lee, Suzanne Wahab, Nujhat Ahmed, Jacob L. Fine, Joanna Derynck, Shuye Pu, Marcelo Ponce, Edyta Marcon, Zhaolei Zhang, Jack F. Greenblatt, Ronald E. Pearlman, , Jeffrey Fillingham

The paper identifies RebL1 as an orthologue of human RBBP4/7 in Tetrahymena thermophila, showing its role in epigenetic regulation and oncogenic functions across species.

Nucleic Acids Research · May 4, 2021Peer-reviewedMolecular Biology