Julia Schaeffer

This study characterizes ribosome heterogeneity in adult mouse organs using proteomics, revealing tissue-specific ribosomal protein (RP) signatures and translational regulation of RP expression.

This study shows that axon guidance defects prevent functional recovery in CNS regeneration and that suppressing Slit/Robo signaling enables axons to reinnervate the SCN, leading to behavioral recovery.

This study identifies the RSK2-RPS6 axis as essential for preconditioning and regeneration in both PNS and CNS neurons, showing its role in axon growth and functional recovery.

The paper uses quantitative proteomic analysis to identify guidance molecules and associated factors in the adult visual system, revealing their potential role in axon guidance during CNS regeneration.

The paper proposes using adult retina explants as an ex vivo model to study axon regeneration in the mature CNS, offering advantages over in vitro and in vivo approaches.

This study identifies protein disulphide isomerase as a key mediator of axon repulsion barriers in somites, showing its role in nitric oxide signaling and growth cone regulation.

The paper shows that ribosomal proteins are synthesized locally in axons and incorporated into ribosomes in a nucleolus-independent manner, regulated by a novel RNA motif.