Author
University of CambridgeORCID 0000-0002-7751-1082Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Ha H. Nguyen, Noortje Kersten, Chun Hei Li…·Ginny G. Farı́as
The paper identifies a mechanism where axonal ER couples translation and secretion of transmembrane proteins to support axonal development.
Chun Hei Li, Noortje Kersten, Nazmiye Özkan…·Ginny G. Farı́as
The paper develops POTATOMap to study biosynthetic lysosomal protein trafficking in neurons, revealing domain-specific mechanisms and interactions.
Max Koppers, Nazmiye Özkan, Ha H. Nguyen…·Ginny G. Farı́as
This study identifies axonal ER tubules and P180/RRBP1 as regulators of local mRNA translation in axons, showing their role in ribosome interactions and proteome dynamics.
Toshiaki Shigeoka, Max Koppers, Hovy Ho‐Wai Wong…·Christine E. Holt
The paper shows that ribosomal proteins are synthesized locally in axons and incorporated into ribosomes in a nucleolus-independent manner, regulated by a novel RNA motif.
Max Koppers, Roberta Cagnetta, Toshiaki Shigeoka…·Christine E. Holt
The paper shows that receptor-ribosome coupling enables selective mRNA translation in axons in response to guidance cues, with receptor-specific interactomes mediating this process.