Toshiaki Shigeoka

The paper shows that chromatin accessibility and co-factor availability determine ASCL1's ability to reprogram cells across different tissues in Xenopus embryos.

This study identifies Zbtb38 as a transcriptional activator of XIAP, showing its role in regulating apoptosis during development and cancer, with implications for therapeutic targeting.

The paper shows that ribosomal proteins are synthesized locally in axons and incorporated into ribosomes in a nucleolus-independent manner, regulated by a novel RNA motif.

The paper shows that receptor-ribosome coupling enables selective mRNA translation in axons in response to guidance cues, with receptor-specific interactomes mediating this process.