Developmental BiologybioRxivPreprint
Transcriptomics, Regulatory Syntax, and Enhancer Identification in Heterogenous Populations of Mesoderm-Induced ESCs at Single-Cell Resolution
Mamduh Khateb, Jelena Perovanović, Kyung Dae Ko…·Vittorio Sartorelli
This study uses bulk and single-cell assays to analyze gene expression, histone modifications, and chromatin features in ESCs transitioning to mesoderm lineages, identifying cis-regulatory elements and transcription factors involved in lineage specification.
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