Author

Kyung Dae Ko

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Stefania Dell’OrsoiD· 2 shared Vittorio SartorelliiD· 2 shared Aster H. Juan· 1 shared Astrid D. Desiree HaaseiD· 1 shared James Simone· 1 shared Jelena PerovanovićiD· 1 shared Jérome ChaliD· 1 shared Kan Jiang· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersDevelopmental Biology

Stefania Dell’OrsoORCID

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2 papers

Recent·Most cited

Transcriptomics, Regulatory Syntax, and Enhancer Identification in Heterogenous Populations of Mesoderm-Induced ESCs at Single-Cell Resolution

Mamduh Khateb, Jelena Perovanović, Kyung Dae Ko, Kan Jiang, Xuesong Feng, Natalia Acevedo-Luna, Jérome Chal, Veronica Ciuffoli, Pavol Genzor, James Simone, Astrid D. Desiree Haase, Olivier Pourquié, Stefania Dell’Orso, Vittorio Sartorelli

This study uses bulk and single-cell assays to analyze gene expression, histone modifications, and chromatin features in ESCs transitioning to mesoderm lineages, identifying cis-regulatory elements and transcription factors involved in lineage specification.

bioRxiv · Mar 29, 2022 · PreprintDevelopmental Biology

Integration of a Computational Pipeline for Dynamic Inference of Gene Regulatory Networks in Single Cells

Kyung Dae Ko, Stefania Dell’Orso, Aster H. Juan, Vittorio Sartorelli

The paper introduces an integrated computational pipeline for inferring gene regulatory networks in single cells without prior knowledge, improving accuracy by combining data dimensions and visualizing gene interactions across developmental stages.

bioRxiv · Apr 18, 2019 · PreprintBioinformatics