Ian Brierley

The paper investigates how the 2A protein interacts with the RNA genome of cardioviruses to activate ribosomal frameshifting through structural changes in the RNA.

This paper elucidates the structural basis of how the Cardiovirus 2A protein regulates gene expression by interacting with RNA elements and ribosomes.

This study investigates how the 2A protein of Theilovirus stimulates ribosomal frameshifting by analyzing its interaction with an RNA pseudoknot and using ribosome profiling.

This study shows segmented negative-strand RNA viruses use upstream translation initiation to expand their coding capacity through non-AUG initiation and host mRNA leader sequence appropriation.

This study compares gene expression in virulent and attenuated IBV strains using RNASeq and RiboSeq, revealing differences in transcription, translation, and host response.