Vincent M. Tutino

This study identifies survivin as a mechanosensitive regulator linking ECM stiffness to GBM growth and matrisome remodeling, suggesting it as a therapeutic target.

This paper identifies radiomic features from CT scans that predict neutrophil extracellular trap (NET) enrichment in ischemic stroke clots, which correlates with mechanical thrombectomy success.

This study shows that FAK and p130Cas modulate early transcription and metabolism in response to substrate stiffness using RNA sequencing in mouse cells.

This study evaluates minocycline's neuroprotective effects in an aged female rat MCAO model, finding improved neurologic scores and reduced infarct size with treatment.

The paper uses chromatin data to show JIA risk variants affect innate immunity through enrichment of epigenetic marks in monocytes and macrophages.