Michelle L. Gumz

This study shows that disrupting the circadian clock in kidney cells accelerates ADPKD progression by altering lipid metabolism.

This study identifies age-dependent and tissue-specific changes in the circadian transcriptome of male mice, showing reduced rhythmic gene expression and increased variability in aged tissues.

This paper introduces likelihood-based methods to detect circadian rhythmicity and differential circadian patterns in transcriptomic data, showing improved error control and power in simulations and real data.