Author

Abeda Jamadar

University of Kansas Medical CenterORCID 0000-0002-0887-4613Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Meekha M. VargheseiD· 3 shared Reena RaoiD· 3 shared Viji RemadeviiD· 3 shared Darren P. WallaceiD· 2 shared Haichun YangiD· 2 shared Christopher J. WardiD· 1 shared Indra ChandrasekariD· 1 shared Michelle L. GumziD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersMolecular Biology

Meekha M. VargheseORCID

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3 papers

Recent·Most cited

Pirfenidone treatment attenuates fibrosis in autosomal dominant polycystic kidney disease

Viji Remadevi, Abeda Jamadar, Meekha M. Varghese, Haichun Yang, Sumedha Gunewardena, Darren P. Wallace, Reena Rao

This study shows pirfenidone reduces fibrosis and improves kidney function in ADPKD by targeting myofibroblast activation and ECM production.

JCI Insight · Sep 21, 2026Peer-reviewedMolecular Biology

Myofibroblast- specific autophagy drives cyst growth in autosomal dominant polycystic kidney disease

Abeda Jamadar, Viji Remadevi, Meekha M. Varghese, Haichun Yang, Vedant P. Thakkar, Indra Chandrasekar, Wen‐Xing Ding, Volker H. Haase, Darren P. Wallace, Reena Rao

This study shows that autophagy in myofibroblasts drives cyst growth in ADPKD by promoting paracrine stimulation of epithelial cells, with lactate and HIF1 playing key roles.

Cell Communication and Signaling · Jul 9, 2026Peer-reviewedMolecular Biology

Circadian clock disruption and growth of kidney cysts in autosomal dominant polycystic kidney disease

Abeda Jamadar, Christopher J. Ward, Viji Remadevi, Meekha M. Varghese, Navjotsingh Pabla, Michelle L. Gumz, Reena Rao

This study shows that disrupting the circadian clock in kidney cells accelerates ADPKD progression by altering lipid metabolism.

Journal of the American Society of Nephrology · Oct 14, 2024Peer-reviewedMolecular Biology