Stefan Giselbrecht

This study models sex differences in liver metabolism using human iPSC-derived organoids exposed to sex-specific hormones, showing sex-specific metabolic profiles and drug metabolism differences.

The paper introduces a thyroid-on-chip platform using mouse embryonic stem cell-derived thyroid organoids to dynamically screen endocrine disrupting chemicals (EDCs) and identify molecular signatures of thyroid disruption.

This study develops a 3D thyroid in vitro model using microfluidic bioprinting to test endocrine disruptors and assess their effects.

This study shows CTCF has dual roles in early mammalian development: promoting morphogenesis through promoter binding early on and enabling correct development via looping later.