Author

Jennifer J. Twardowski

University of RochesterORCID 0000-0002-1366-2738Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Stephano S. MelloiD· 2 shared Zamira Guerra SoaresiD· 2 shared A. M. Zakaria KhaniD· 1 shared Alexander MuiriD· 1 shared B. Turner· 1 shared Bradley N. Mills· 1 shared Bradley SmithiD· 1 shared Brian James AltmaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Stephano S. MelloORCID

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2 papers

Recent·Most cited

Cancer BiologyNaturePeer-reviewedMar 18, 2026

Catabolism of extracellular glutathione supplies amino acids to support tumor growth

Fábio Hecht, Marco Zocchi, Emily T. Tuttle…·Isaac S. Harris

This study shows that extracellular glutathione supports tumor growth by providing amino acids through catabolism, and inhibiting this process slows tumor growth.

28 citationstop 1%

humanexperimental assay

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Cancer BiologybioRxivPreprintMay 29, 2024

Drug-Induced p53 Activation Limits Pancreatic Cancer Initiation

Jennifer J. Twardowski, Thomas I. Heist, Zamira Guerra Soares…·Stephano S. Mello

This study shows that stabilizing wild-type p53 with Nutlin-3a reduces ADM and PanIN formation in a KrasG12D mouse model by promoting acinar cell differentiation.

3 citations

mouseexperimental assay

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