Yao Li

Decision benchmarking reveals when protein foundation models add experimental value

This paper benchmarks decision strategies for protein engineering, showing when models and measurements improve decisions based on accumulated evidence.

Molecular basis of vitamin K-dependent protein γ-glutamyl carboxylation

This study reports cryo-EM structures of GGCX bound to VKDPs and vitamin K, revealing its dual-catalytic mechanism and disease-associated mutation clusters.