Marie-Pierre Sanchez

Integrating pangenome and imputation framework reveals structural variants affecting stature and milk composition traits in French dairy cattle

The paper integrates long-read, short-read, and SNP data using a pangenome and imputation framework to identify structural variants associated with stature and milk traits in dairy cattle.

A comprehensive genetic study of the vaginal microbiota composition of Holstein cows

This study investigates the genetic influence on bovine vaginal microbiota composition and identifies heritable traits and genetic correlations with fertility and production traits in Holstein cows.

Genome-wide meQTL mapping in cattle blood reveals cis and trans regulation of DNA methylation

This study maps cis and trans meQTLs in cattle blood DNA methylation using EpiChip data, identifying regulatory genes and hotspots associated with methylation patterns.

A novel reusable transcriptome-wide association study workflow used to map key genes linked to important cattle traits

The paper presents a reusable TWAS workflow for cattle to identify gene-trait associations using GWAS and transcriptomic data, improving variant calling and detecting novel associations.

Assembly of a pangenome uncovers novel non-reference unique insertion sequences in cattle highlighting their genetic diversity

The paper constructs a cattle pangenome to identify novel non-reference unique insertions (NRUIs) and links them to economically important traits.

Comprehensive detection of structural variations in long and short reads dataset of French cattle

The paper detects structural variants in French cattle using long and short-read data, identifying 25,191 deletions and 30,118 insertions across 14 breeds.

Application of a French cattle pangenome, from structural variant discovery to association studies on key phenotypes

The paper constructs a bovine pangenome using long-read sequencing and identifies structural variants associated with key phenotypes in French cattle breeds.