The paper develops a streamlined workflow for proteomic analysis of proteins and PTMs from dried blood, demonstrating feasibility and best practices for MS-based quantification.

Journal of Proteome Research · Jun 5, 2026Peer-reviewedBiochemistry

Mass spectrometry-based quantification of proteins and post-translational modifications in dried blood: longitudinal sampling of patients with sepsis in Tanzania

Matthew W. Foster, T. McMahon, James S. Ngocho, Asia Hemed Kipengele, Marlene J. Violette, Youwei Chen, Deng B. Madut, Robert S. Plumb, A. lan Wong, Lingye Chen, Grace M. Lee, Philoteus A. Sakasaka, Blandina Theophil Mmbaga, John A. Crump, Micah T. McClain, , Matthew P. Rubach

The paper quantifies proteins and post-translational modifications in dried blood from sepsis patients in Tanzania, revealing proteome signatures of inflammation and correlations with clinical markers.

PROTEOMICS · Dec 3, 2025Peer-reviewedSystems Biology

Estrogen accelerates heart regeneration by promoting inflammatory responses in zebrafish

Shisan Xu, Fangjing Xie, Li Tian, Samane Fallah, Fatemeh Babaei, Sinai H. C. Manno, Francis A. M. Manno, Lina Zhu, Kin Fung Wong, Yimin Liang, Rajkumar Ramalingam, Lei Sun, Xin Wang, Robert S. Plumb, Lee A. Gethings, , Shuk Han Cheng

This study shows estrogen accelerates heart regeneration in zebrafish by enhancing inflammatory responses, which can be modulated by estrogen antagonists.

Journal of Endocrinology · Jan 28, 2020Peer-reviewedDevelopmental Biology