Author

Lina Zhu

City University of Hong KongORCID 0000-0002-8558-2120Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lina Zhu1 paper · Wenzhou City People's Hospital

Biology Disciplines

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Genomics· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Xin WangiD· 2 shared Adrian F. OchsenbeiniD· 1 shared Adriana K. AlexanderiD· 1 shared Adrienne VancuraiD· 1 shared Álvaro AndradesiD· 1 shared Andrea Kobel· 1 shared Andrés LanzósiD· 1 shared Carlos Pulido-QuetglasiD· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Xin WangORCID

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3 papers

Recent·Most cited

Multi-hallmark long noncoding RNA maps reveal non-small cell lung cancer vulnerabilities

Roberta Esposito, Taisia Polidori, Dominik F. Meise, Carlos Pulido-Quetglas, Panagiotis Chouvardas, Stefan Forster, Paulina Schaerer, Andrea Kobel, Juliette Schlatter, Erik Kerkhof, Michaela Roemmele, Emily S. Westemeier-Rice, Lina Zhu, Andrés Lanzós, Hugo Guillen-Ramirez, , Rory Johnson

The paper identifies 60 high-confidence oncogenic lncRNAs in NSCLC using CRISPR deletion screens and ASO validation, revealing therapeutic vulnerabilities.

Cell Genomics · Aug 22, 2022Peer-reviewedGenomics

Meiotic gene transcription programs are mediated by A-MYB and BRDT-dependent RNA polymerase II pause release during mammalian prophase I

Adriana K. Alexander, Edward J. Rice, Gilad Barshad, Lina Zhu, Paula E. Cohen, Charles G. Danko

The paper investigates how A-MYB and BRDT regulate RNA polymerase II pause release during meiotic prophase I, linking transcriptional bursts to chromatin changes and recombination.

bioRxiv · Aug 19, 2022 · PreprintGenomics

Estrogen accelerates heart regeneration by promoting inflammatory responses in zebrafish

Shisan Xu, Fangjing Xie, Li Tian, Samane Fallah, Fatemeh Babaei, Sinai H. C. Manno, Francis A. M. Manno, Lina Zhu, Kin Fung Wong, Yimin Liang, Rajkumar Ramalingam, Lei Sun, Xin Wang, Robert S. Plumb, Lee A. Gethings, , Shuk Han Cheng

This study shows estrogen accelerates heart regeneration in zebrafish by enhancing inflammatory responses, which can be modulated by estrogen antagonists.

Journal of Endocrinology · Jan 28, 2020Peer-reviewedDevelopmental Biology