Brett S. Phinney

The paper develops membrane-targeted TurboID variants for in vivo proteomics in neuronal circuits, identifying subcellular proteins and their changes during acute drug exposure.

The paper develops a streamlined workflow for proteomic analysis of proteins and PTMs from dried blood, demonstrating feasibility and best practices for MS-based quantification.

This study identifies CBL as a regulator of antiviral and antibacterial responses during M. tuberculosis infection by suppressing antiviral effector genes and modulating ubiquitin-mediated signaling.

This paper introduces ProPPr, a method for proteomic profiling of phospho-tau aggregates in tauopathies, revealing common and disease-specific proteins associated with these lesions.

The paper identifies a calcium-dependent pathway involving ALIX that links lysosomal damage to stress granule formation, promoting cell survival in response to various stressors.

This study shows ATG5 and membrane atg8ylation regulate retromer function in GLUT1 trafficking, independent of canonical autophagy.

The paper compares different LC-MS/MS platforms and data acquisition strategies for detecting genetically variant peptides in human hair shafts to improve proteomic genotyping.

The paper evaluates DIA performance across multiple laboratories using standardized samples and provides benchmark datasets for education and tool development.

The paper uses deep learning and Prosit to enhance proteome profiling of grapevine vascular sap during Pierce's disease, increasing identified proteins and revealing new pathways.

The paper identifies under-reported metabolic genes as potential drug targets in ERneg breast tumors using multi-omics data and text mining.