ImmunologybioRxivPreprint
Interleukin 22 mediates interleukin 23-induced pathology in newborn mice by disrupting the function of pancreatic and intestinal cells
Glaucia C. Furtado, Lili Chen, Valentina Strohmeier…·Sergio A. Lira
This study shows that IL-23-induced pathology in newborn mice is mediated by IL-22, which disrupts pancreatic and intestinal cell function, leading to malabsorption and early death.
DOI 10.1101/346577