Author

Joris H. Hageman

University Medical Center UtrechtORCID 0000-0002-1386-054XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Hugo J.G. SnippertiD· 2 shared Julian R. Buissant des AmorieiD· 2 shared Sascha R. BrunneriD· 2 shared Aleksandra BalwierziD· 1 shared Defne Yalçin· 1 shared Dimitrios LaskarisiD· 1 shared Franziska L. Langner· 1 shared Hans C. CleversiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Hugo J.G. SnippertORCID

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2 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedJul 22, 2025

Mature tuft cell phenotypes are sequentially expressed along the intestinal crypt-villus axis following cytokine-induced tuft cell hyperplasia

Julian R. Buissant des Amorie, Max A. Betjes, Jochem H. Bernink…·Hugo J.G. Snippert

The paper identifies sequential transcriptomic states of tuft cells along the intestinal crypt-villus axis and shows cytokine-specific differentiation into distinct tuft cell phenotypes.

18 citationstop 2%

mousehuman

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Cell BiologybioRxivPreprintJul 13, 2025

Stem cells actively suppress regenerative plasticity in human colon

Joris H. Hageman, Defne Yalçin, Julian R. Buissant des Amorie…·Hugo J.G. Snippert

The paper investigates human colon stem cell function, showing they suppress regenerative plasticity by producing retinoic acid, which inhibits the regenerative response in colonocytes.

3 citations

humanorganoid / primary culture

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