Author
Royal Netherlands Academy of Arts and SciencesORCID 0000-0001-9332-9224Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Li Yang, Lulu Huang, Fenna L. H. van Rijt…·Claudia Y. Janda
This paper develops a Wnt-IL-13 fusion protein that activates tuft cells to enhance intestinal regeneration in human organoids.
Julian R. Buissant des Amorie, Max A. Betjes, Jochem H. Bernink…·Hugo J.G. Snippert
The paper identifies sequential transcriptomic states of tuft cells along the intestinal crypt-villus axis and shows cytokine-specific differentiation into distinct tuft cell phenotypes.
Astrid Cleven, Angelo D. Meringa, Péter Brázda…·Zsolt Sebestyén
This study shows that single mutations during early oncogenesis can upregulate BTN2A1, enabling Vγ9Vδ2 TCR binding, but full activation requires subsequent phosphorylation of BTN3A1.
Lulu Huang, Jochem H. Bernink, Amir Giladi…·Hans C. Clevers
The paper identifies four human tuft cell states, showing they function as radiation-resistant stem cells capable of regenerating the intestinal epithelium.