Author

Christine Jaxel

Centre National de la Recherche ScientifiqueORCID 0000-0002-1387-4458Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Cédric MontignyiD· 2 shared Guillaume LenoiriD· 2 shared Alenka ČopičiD· 1 shared Ana Rita Dias AraújoiD· 1 shared Bertrand Arnou· 1 shared Camille SyskaiD· 1 shared Cécile HilpertiD· 1 shared Hafez RazmazmaiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Cédric MontignyORCID

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2 papers

Recent·Most cited

Ist2, a protein involved in phosphatidylserine transport, is an ER lipid scramblase

Heitor Gobbi Sebinelli, Camille Syska, Hafez Razmazma, Véronique Albanèse, Ana Rita Dias Araújo, Cécile Hilpert, Cédric Montigny, Christine Jaxel, Manuella Tchamba, Karolina Belingar, Juan Martín D’Ambrosio, Luca Monticelli, Guillaume Lenoir, Alenka Čopič

This study identifies Ist2 as the first dedicated ER phospholipid scramblase in yeast and shows its role in ER membrane remodeling.

bioRxiv · Feb 13, 2025 · PreprintCell Biology

The SERCA residue Glu340 mediates inter-domain communication that guides Ca2+ transport

Maxwell M. G. Geurts, Johannes D. Clausen, Bertrand Arnou, Cédric Montigny, Guillaume Lenoir, Robin Adam Corey, Christine Jaxel, JESPER VUUST MØLLER, Poul Nissen, Jens Peter Andersen, Marc le Maire, Maike Bublitz

The paper investigates the role of Glu340 in SERCA's inter-domain communication, showing that the E340A mutation slows Ca2+ binding kinetics and alters structural dynamics.

Proceedings of the National Academy of Sciences · Nov 23, 2020Peer-reviewedMolecular Biology