Christian Woehle

Minimizing time in culture: A prototypic autologous manufacturing workflow for monoclonal iPSC lines within seven weeks

This study develops a time-efficient, standardizable workflow for generating monoclonal iPSC lines from human skin biopsies within seven weeks, with low variability and genomic integrity.

MITE infestation of germline accommodated by genome editing in Blepharisma

The paper analyzes IESs in Blepharisma stoltei, revealing MITEs as a major source of IESs and challenging current models of transposon domestication in ciliates.

Genome editing excisase origins illuminated by somatic genome of Blepharisma

The paper reports the somatic genome of Blepharisma stoltei, identifying a PiggyBac transposase homolog as a potential IES excisase, suggesting an evolutionary origin for genome editing.

Biodiversity genomics of small metazoans: high quality de novo genomes from single specimens of field-collected and ethanol-preserved springtails

This study generates high-quality de novo genomes from single ethanol-preserved springtail specimens using a new amplification-based protocol, achieving over 95% BUSCO completeness.