Author

Lance W.Q. Xu

Arizona State UniversityORCID 0000-0002-1413-1007Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:imaging· 3 Approach:Bayesian inference· 2 Approach:deep learning· 2 Approach:statistical model· 2 Research Focus:trajectory inference· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:deconvolution· 1

Frequent Co-Authors

Steve PresséiD· 4 shared Aleksandra RađenovićiD· 2 shared Ayush SaurabhiD· 2 shared David ŠťastnýiD· 2 shared Marianna Fanouria MitsioniiD· 2 shared Martin HofiD· 2 shared Mohamadreza FazeliD· 2 shared Nathan RoncerayiD· 2 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersBiophysics

Steve PresséORCID

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Author profile →

4 papers

Recent·Most cited

Highly multiplexed spectral FLIM via physics informed data analysis

Mohamadreza Fazel, Reza Hoseini, Ayush Saurabh, Lance W.Q. Xu, Lorenzo Scipioni, Giulia Tedeschi, Enrico Gratton, Michelle A. Digman, Steve Pressé

This paper introduces a Bayesian S-FLIM framework that learns spectra and lifetimes photon-by-photon, enabling efficient deconvolution of up to 9 fluorophore species with overlapping spectra.

bioRxiv · Aug 4, 2025 · PreprintBiophysics

Particle Tracking for Quantized Intensities Accelerated with Parallelism

Lance W.Q. Xu, Nathan Ronceray, Marianna Fanouria Mitsioni, Titouan Brossy, David Šťastný, Radek Šachl, Martin Hof, Aleksandra Rađenović, Steve Pressé

QTrack improves particle tracking by directly modeling quantized photon detections, achieving faster and more accurate results than traditional methods.

bioRxiv · May 30, 2025 · PreprintBiophysics

Accurate tracking of lytic granules via simultaneous particle tracking, phase retrieval and point spread function reconstruction

Mohamadreza Fazel, Reza Hoseini, Maryam Sadat Mahmoodi, Kevin L. Scrudders, Ayush Saurabh, Lance W.Q. Xu, Zeliha Kilic, Behshid Kasmaie, Mingdong Liu, Douglas P. Shepherd, Shalini T. Low-Nam, Fang Jiong Huang, Steve Pressé

This paper develops a framework for simultaneous particle tracking, phase retrieval, and PSF reconstruction to improve 3D tracking of lytic granules in T cells.

bioRxiv · May 2, 2025 · PreprintBiophysics

Tracking Without Linking or Localization: Single-Photon Tracking

Lance W.Q. Xu, Nathan Ronceray, Marianna Fanouria Mitsioni, Titouan Brossy, David Šťastný, Jay C. Spendlove, Radek Šachl, Martin Hof, Aleksandra Rađenović, Steve Pressé

This paper introduces SP2T, a method for tracking fast-diffusing particles using 1-bit image data, showing it outperforms traditional methods and enables faster, more accurate tracking.

bioRxiv · Jan 10, 2025 · PreprintBiophysics