Martin Hof

This study quantifies lipid sorting during clathrin-mediated endocytosis and finds that lipid asymmetry in the plasma membrane explains observed partitioning, with minimal selectivity for cytoplasmic leaflet lipids compared to non-vesicular trafficking.

This paper shows FGF2 oligomerization drives PI(4,5)P2 partitioning and membrane pore formation, enabling FGF2 translocation across the plasma membrane.

The paper quantifies lipid transport between organelles in mammalian cells, revealing non-vesicular transport as a key mechanism for species-specific lipid sorting.

QTrack improves particle tracking by directly modeling quantized photon detections, achieving faster and more accurate results than traditional methods.

The paper revises the diffusion law to quantify nanoscale membrane organization parameters using STED-FCS data, validating the Saffman-Delbruck assumption for lipid diffusion.

This study investigates Galectin-1's specificity for GM1 over GD1a in lipid membranes and finds no evidence of cross-linking by homodimers.

This paper introduces SP2T, a method for tracking fast-diffusing particles using 1-bit image data, showing it outperforms traditional methods and enables faster, more accurate tracking.

The paper investigates whether calmodulin binds to lipids in the cytosolic leaflet of plasma membranes and finds that CaM interacts with PS and PE, with calcium inducing conformational changes and affecting membrane charge and stability.