Russell E. Jacobs

Induction of ferroptotic and amyloidogenic signatures linked to Alzheimers disease by chemically distinct air pollutants

This study shows that metal-rich air pollutants induce ferroptosis and amyloidogenic pathways linked to Alzheimer's disease through shared transcriptional and oxidative mechanisms.

Quality Assurance Strategies for Brain State Characterization by MEMRI

The paper introduces quality assurance strategies and software for MEMRI data analysis to enable scalable and reproducible brain state characterization across cohorts.

Reconfiguration of Brain-Wide Neural Activity After Early Life Adversity

This study uses MEMRI to show that early life adversity alters brain-wide neural activity in mice, with context-dependent changes in multiple brain regions after threat exposure.

A model of traumatic brain injury using human iPSC-derived cortical brain organoids

This study uses high-intensity focused ultrasound to induce traumatic brain injury in human iPSC-derived cortical organoids, revealing key pathological features like tau phosphorylation and neurodegeneration.

Tcf12 controls dynamic calvarial bone growth and motor learning in mice

This study investigates the role of Tcf12 in calvarial bone development and motor learning in mice, finding that Tcf12 loss leads to altered bone formation and impaired motor learning.

Harnessing axonal transport to map reward circuitry: Differing brain-wide projections from medial forebrain domains

This study maps brain-wide projections from medial forebrain domains using Mn(II) tracers, revealing distinct pathways from anterior cingulate and infralimbic/prelimbic areas.